HEALTH CHECKS
Over 40 Health Check — What Should You Be Testing?
A guide to midlife preventive health review, including cardiovascular, metabolic and hormonal assessment for patients over 40.
Midlife is the point at which many preventive health risks become more relevant. Cardiovascular disease, metabolic syndrome, diabetes, hormonal change and certain cancers all have risk profiles that begin to shift after 40.
An over-40 health check is not about assuming something is wrong. It is about understanding where you stand so that future risk can be managed earlier and more sensibly.
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What an over-40 check may assess
Blood pressure and cardiovascular risk. Cholesterol and lipid profile. Diabetes markers including fasting glucose and HbA1c. Thyroid function. Liver and kidney function. Hormone levels — including menopause markers in women and testosterone in men. Nutritional markers including iron, B12, and vitamin D. Weight, BMI and body composition. Family history and lifestyle risk assessment.
Women
Why midlife review matters for women
The years around 40 often coincide with perimenopause, which can affect sleep, mood, energy, weight and cycle regularity. A midlife check can help clarify whether symptoms are hormonal, metabolic, or both. Where relevant, this may link with women’s health or a Well Woman Check.
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Men
Why midlife review matters for men
For men, midlife is when cardiovascular risk, testosterone decline, prostate-related concerns and metabolic health become more relevant. A Well Man Check or targeted men’s health assessment may be appropriate.
Common questions
Does a health check become more important after 40 than before?
It tends to become more clinically useful. Cardiovascular risk, metabolic shifts and hormonal change become more relevant from midlife, so a structured review at this stage often identifies trends early enough to manage without more intensive intervention later. Under 40, screening can still be useful with a strong family history or specific concerns.
Should hormonal testing be part of a midlife health check?
Often, yes. For women, perimenopause may affect sleep, mood, energy, weight and cycle — hormone testing can help separate this from thyroid or metabolic contributors. For men, testosterone assessment may be relevant where energy, libido or central weight gain have shifted. Whether it is included depends on symptoms and context.
How is an over-40 health check different from a Well Man or Well Woman Check?
They overlap. The over-40 review is broadly focused on midlife cardiovascular, metabolic and hormonal shifts regardless of sex. A Well Man or Well Woman Check structures the same conversation around sex-specific concerns — prostate and testosterone, or menstrual and menopausal markers — alongside the shared metabolic core.
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