PRF TREATMENT
PRF for Hair Loss
What PRF is, who it may suit, and how it fits alongside other hair loss treatment options.
PRF (platelet-rich fibrin) is a regenerative treatment prepared from the patient’s own blood. It concentrates platelets, growth factors and fibrin into a matrix that can be applied to the scalp as part of a hair-loss treatment plan. Unlike many hair-loss products, PRF uses the body’s own biological material rather than a synthetic drug — which appeals to patients seeking a more natural approach. However, it is not a standalone cure, and its role in hair restoration is best understood as one option within a broader clinical pathway that may also include blood tests, prescription medication, lifestyle adjustment, or monitoring.
Understanding what PRF can realistically offer — and who it may suit — helps patients make informed decisions.
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How PRF works for hair
A small sample of blood is taken and centrifuged to separate its components. The resulting PRF concentrate contains a high density of platelets embedded in a fibrin matrix, along with growth factors (including PDGF, TGF-β, VEGF and others) that are released slowly over time. When applied to the scalp — typically via micro-injections into areas of thinning — the growth factors are thought to stimulate dormant follicles, support the growth phase of the hair cycle, and improve blood supply to the scalp. The fibrin matrix provides a scaffold for sustained release, which is one of the key differences from older PRP preparations.
Suitability
Who PRF may suit
PRF may be discussed for patients with early to moderate male pattern or female pattern hair loss who want a treatment option alongside or instead of medication. It may also be considered for patients who have had some response to minoxidil or finasteride but want additional support.
PRF is generally not considered appropriate for patients with advanced hair loss where follicles have been lost entirely, for certain autoimmune hair conditions, or for patients with significant blood disorders or active scalp infections.
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What a treatment course involves
PRF for hair typically involves a series of sessions — commonly 3 to 4 treatments spaced several weeks apart — followed by maintenance sessions at longer intervals. Each appointment involves a blood draw, preparation of the PRF concentrate, and micro-injection into the scalp. The process takes 30–60 minutes. Some scalp tenderness is normal afterwards but usually settles within a day or two. Results are gradual and are best assessed over months rather than weeks — what to expect after PRF treatment covers this in more detail.
Setting expectations
Realistic expectations
PRF is not a guaranteed treatment and results vary between patients. Some see meaningful improvement in hair density and thickness. Others see more modest changes. Some do not respond significantly. The evidence base is growing but not yet as established as for finasteride or minoxidil.
That is why PRF is best discussed within a clinical consultation where the likely cause of hair loss has been assessed, realistic expectations have been set, and the treatment is positioned as part of a broader plan. See PRF treatment for the full service page and hair restoration for the assessment-led pathway.
Common questions
What does a PRF treatment for hair loss actually involve?
Platelet-rich fibrin (PRF) is prepared from a small blood sample taken at the appointment, processed to concentrate growth factors, then injected into specific areas of the scalp. The treatment is delivered at Basuto in-clinic and typically takes around an hour including preparation. It is considered as part of a clinical assessment rather than a stand-alone cosmetic treatment.
Who is PRF most suitable for?
PRF is usually considered for patients with early to moderate pattern hair loss or diffuse thinning where the clinical assessment suggests it may help, and where expectations are realistic about what the treatment can do. It is not appropriate for every type of hair loss; assessment first, treatment second.
How many PRF sessions are typically considered?
A course of sessions spaced over several weeks is usual, followed by maintenance sessions depending on response. The GP explains the likely schedule at the consultation rather than committing to a fixed package up front.
FURTHER READING